Development And Validation Of HPLC Method For Determination Of
Bortezomib In Pharmaceutical Preparation

Lincy Joseph*Mathew George 1, Akshay Kumar 2, Surekha SR1
Page No. 19-32

In this work an assay method for Bortezomib and its validation by using HPLC was carried out.
Bortezomib is a new drug not much analytical work is done over it. And it is an anticancer drug and
is very toxic too. So an adequate estimation of drug in dosage forms is very essential. So here we
will develop and validate HPLC method to estimate Bortezomib available in injection form. We will
develop an accurate, reliable and economical method to estimate Bortezomib.
Key-word : Bortezomib, HPLC validation, UVspectrophotometer, precision, accuracy.