Potential Health Benefits and Adverse Effects Associated with Phytate in Foods: A Review

Habtamu Fekadu Gemede1, 2
Page No.19-31

Phytate (myo-inositol (1,2,3,4,5,6) hexakisphosphate), a naturally compound formed during
maturation of plant seeds and grains is a common constituent of plant-derived foods. This paper is
aimed to review the scientific information concerning the potential health benefits and adverse
effects associated with phytate in foods. The adverse health effects of phytate in the diet is its effect
on mineral uptake. Minerals of concern in this regard would include Zn2+, Fe2+/3+, Ca2+, Mg2+,
Mn2+, and Cu2+. Especially zinc and iron deficiencies were reported as a consequence of high
phytate intakes. In addition, a the adverse effect on the nutritional value of protein by dietary
phytate is discussed. Consumption of phytate, however, seems not to have only adverse health
effects but also potential benefits on human health. Dietary phytate was reported to prevent kidney
stone formation, protect against diabetes mellitus, caries, atherosclerosis and coronary heart
disease as well as against a variety of cancers.
Keywords : Antinutrient, Phytate, Health Benefits, Health Effects, Human Nutrition.