Changes in QT interval during hemodialysis

Khanoussi Ayoub* , Naciri M , Alaoui Handira.C , Ossil.M, Fadili W , Laouad.I
Page No. 61-66

Mortality cardiovascular and morbidity are high in chronic renal failure patients,the QT interval
corrected for heart rate predispose to ventricular arrhythmias and sudden death.The aim of our
work is to evaluate the effect of hemodialysis on interval QT and his dispersion in chronic
hymodialysed patients.Fourty-seven chronic hemodialysis patients were assessed by a standard
examination including blood pressure,body weight,heart rate,12-lead electrocardiogram and a
serum electrolytes (Na+,K+,Ca++,phosphate) urea,creatinine,30min before and after hemodialysis.
QT and QTc interval QTc=QT/√RR (in milliseconds [ms]) for each electrocardiogram were
manually measuread by the same observer.The difference between the maximum and minimum QT
was noted as QT dispersion (QT d).Our results confirm that metabolic changes during hemodialysis
can lead to a substantial risk of cardiac arrhythmias.