Liver nodules and acute renal failure in multiple myeloma Revealed

Zineb AIT LAHCEN*, Imane ESQALLI*, Fatimaezzahra KARIMI*,Wafaa FADILI*,
Inass LAOUAD*
Page No. 43-46

Extramedullary involvement in myeloma is very rare, especially liver involvement .Extramedullary
involment may be the result of a plasma cell infiltration, deposits of light chains(by analogy to renal
tubulopathy) or ALamyloidosis associated with my eloma.Hepatomegaly can be observedin POEMS
syndrome (polyneuropathy, organomegaly, endocrinopathy, monoclonalgammopathy, and skin
changes)[1].We report the case of a patient aged 52,admitted for asthenia, palor, and hepatomegaly
as primary manifestations of multiple myeloma and in whom the diagnosis of multiple hepatic
nodules secondary to myeloma was made.
Keyword : Multiple myeloma - liver nodule - acute renal insufficiency.