Epidemiological profile of glomerular kidney disease in Morocco

Zineb AIT LAHCEN1,Fatimaezzahra KARIMI1, Sara Fassil1,Wafaa FADILI1, Inass
LAOUAD1
Page No. 36-42

The epidemiological approach of glomerular diseases is still underdeveloped in our country. The
aim of our study is to know the frequency of glomerular nephropathies in our context, describe their
different demographic, clinical and biological, and their etiological and evolutionary profile. We
conducted a retrosprctive study in the nephrology department of the university hospital Mohammed
VI, between January 2009 and December 2015. We collected 550 patients including 284 men
(51.63 percent). The average age at diagnosis was 30.2 +/- 13.6 years. The clinical picture was
dominated by the edematous syndrome (88.5 percent), hematuria (63.2 percent) and hypertension (37.3percent).
Glomerular nephritis were primitive in 61.2 percent of cases, the glomerulopathy with minimal
glomerular lesions and membranoproliferative glomerulonephritis accounted for the most common
histological types with respectively 37.8 percent and 21.2 percent of cases. Secondary glomerular nephritis
were for 38.8 percent of cases, their etiologies were dominated by lupus nephritis (65percent), infectious
diseases (10percent) and vasculitis (12.5percent). 78percent of our patients received symptomatic treatment, the
extra renal purification was indicated in 20percent of cases. In primitive glomerulopathies the use of
corticosteroids alone was proposed in 50.7 percent of cases and corticosteroids associated with immuno
suppressive in 18.6 percent of cases. Complete remission was achieved in 44.3 percent of cases, and partial
remission in 25.8percent, treatment failure was noted in 11.2 percent and renal death in 15.7 percent of cases.
Keyword : glomerular nephropathy- Epidemiology- Adult- renal biopsy.