Genetic predisposition to lymph node tuberculosis, study of polymorphism of a candidate discomfort: MBL2.

S. OURAINI[1], I. NAKKABI[2], F. BENARIBA[3]
Page No. 13-20

The WHO estimates that between 2000 and 2020, nearly one billion people will be newly infected
with TB, 200 million of them develop the disease 35 million will die if no progress is made in the
control infection.[1].The identification of genetic factors predisposing to tuberculosis is
fundamental to understanding the pathophysiology of this disease and allow the development of
new vaccines and therapeutic strategies. Several studies have focused on the gene polymorphism
MBL2 [2,3,4] and its association with the pulmonary form of TB. In this work, we will be of interest
to the MBL2 gene polymorphism research in a population of 10 children with lymph node
tuberculosis.
Keywords : lymph node tuberculosis, MBL2 gene.